Major structural proteins of type B, type C, and type D oncoviruses share interspecies antigenic determinants.

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Major structural proteins of type B, type C, and type D oncoviruses share interspecies antigenic determinants.

Interspecies antigenic determinants have been used as markers to study the evolution of oncoviruses. By radioimmunologic techniques, it has been possible to detect crossreactivities among the major structural proteins of prototype viruses representing each of the three major Oncovirinae genera. Two different subsets of interspecies antigenic determinants were demonstrated. One encompasses known...

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Interspecies antigenic determinants of the reverse transcriptases and p30 proteins of mammalian type C viruses.

The major internal structural proteins (p30) of type C viruses isolated from several mammalian species were studied by radioimmunoprecipitation and competitive radioimmunoassays. Three antigenically distinguishable sets of interspecies determinants could be demonstrated by both methods. One set of determinants shared by viruses of rodent origin (mouse and rat) can be detected readily in feline ...

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Endogenous New World primate retrovirus: interspecies antigenic determinants shared with the major structural protein of type-D RNA viruses of Old World monkeys.

A reverse transcriptase-containing virus has recently been isolated from a squirrel monkey (Saimiri sciureus). Molecular hybridization studies demonstrate that the squirrel monkey retrovirus (SMRV) is endogenous to this New World primate, yet lacks detectable nucleotide sequence homology with cellular DNAs of representative Old World primates or with the genomes of previously isolated Old World...

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Species-specific and interspecific antigenic determinants associated with the structural protein of feline C-type virus.

The group-specific protein of feline leukemia viruses has been isolated by isoelectric focusing. This protein has a molecular weight, calculated from sodium dodecyl sulfate-acrylamide gel electrophoresis, of 25,000 and forms a resolved band in such gels when disrupted virions are analyzed. This protein contains both species-specific antigenic determinants, as well as interspecific cross-reactiv...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1980

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.77.1.72